精液质量与体外受精

Semen quality and in-vitro fertilization.

作者信息

Jeyendran R S, Van der Ven H H, Rachagan S P, Perez-Peleaz M, Zaneveld L J

机构信息

Institute of Reproductive Medicine, Chicago, Illinois.

出版信息

Aust N Z J Obstet Gynaecol. 1989 May;29(2):168-72. doi: 10.1111/j.1479-828x.1989.tb01710.x.

DOI:10.1111/j.1479-828x.1989.tb01710.x

PMID:2803129

Abstract

The standard sperm parameters, and a newly developed assay, the hypoosmotic swelling (HOS) test, of 208 ejaculates were correlated with in vitro fertilization (IVF) outcome to assess their predictive value of the fertilizing capacity of spermatozoa. One hundred fifty-three (73.6%) of the ejaculates possessed spermatozoa that fertilized at least one oocyte and were considered fertile. Among the semen parameters studied, only the HOS test had a relatively high (r = 0.46, p less than 0.001) association with the fertilizing capacity of the spermatozoa. This test was also able to predict the outcome of IVF more reliably than the other semen parameters studied.

摘要

对208份射精样本的标准精子参数以及一项新开发的检测方法——低渗肿胀（HOS）试验，与体外受精（IVF）结果进行相关性分析，以评估它们对精子受精能力的预测价值。其中153份（73.6%）射精样本中的精子使至少一个卵母细胞受精，被认为具有生育能力。在所研究的精液参数中，只有HOS试验与精子的受精能力具有相对较高的相关性（r = 0.46，p < 0.001）。该试验在预测IVF结果方面也比所研究的其他精液参数更可靠。