Mandel Ernest I, Bernacki Rachelle E, Block Susan D
Renal Division, Department of Medicine and.
Ariadne Laboratories, Brigham and Women's Hospital and Harvard TH Chan School of Public Health, Boston, Massachusetts.
Clin J Am Soc Nephrol. 2017 May 8;12(5):854-863. doi: 10.2215/CJN.05760516. Epub 2016 Dec 28.
Dialysis-dependent ESRD is a serious illness with high disease burden, morbidity, and mortality. Mortality in the first year on dialysis for individuals over age 75 years old approaches 40%, and even those with better prognoses face multiple hospitalizations and declining functional status. In the last month of life, patients on dialysis over age 65 years old experience higher rates of hospitalization, intensive care unit admission, procedures, and death in hospital than patients with cancer or heart failure, while using hospice services less. This high intensity of care is often inconsistent with the wishes of patients on dialysis but persists due to failure to explore or discuss patient goals, values, and preferences in the context of their serious illness. Fewer than 10% of patients on dialysis report having had a conversation about goals, values, and preferences with their nephrologist, although nearly 90% report wanting this conversation. Many nephrologists shy away from these conversations, because they do not wish to upset their patients, feel that there is too much uncertainty in their ability to predict prognosis, are insecure in their skills at broaching the topic, or have difficulty incorporating the conversations into their clinical workflow. In multiple studies, timely discussions about serious illness care goals, however, have been associated with enhanced goal-consistent care, improved quality of life, and positive family outcomes without an increase in patient distress or anxiety. In this special feature article, we will () identify the barriers to serious illness conversations in the dialysis population, () review best practices in and specific approaches to conducting serious illness conversations, and () offer solutions to overcome barriers as well as practical advice, including specific language and tools, to implement serious illness conversations in the dialysis population.
依赖透析的终末期肾病是一种严重疾病,疾病负担、发病率和死亡率都很高。75岁以上的个体在透析第一年的死亡率接近40%,即使是那些预后较好的人也面临多次住院和功能状态下降的问题。在生命的最后一个月,65岁以上的透析患者比癌症或心力衰竭患者有更高的住院率、重症监护病房入住率、手术率和院内死亡率,同时使用临终关怀服务的比例更低。这种高强度的治疗往往与透析患者的意愿不一致,但由于未能在重病背景下探索或讨论患者的目标、价值观和偏好而持续存在。不到10%的透析患者报告曾与肾病专家讨论过目标、价值观和偏好,尽管近90%的患者表示希望进行这样的谈话。许多肾病专家回避这些谈话,因为他们不想让患者不安,觉得预测预后的能力存在太多不确定性,在开启这个话题的技巧上缺乏信心,或者难以将这些谈话纳入他们的临床工作流程。然而,在多项研究中,关于重病护理目标的及时讨论与增强目标一致的护理、改善生活质量以及积极的家庭结果相关,且不会增加患者的痛苦或焦虑。在这篇专题文章中,我们将()确定透析人群中重病谈话的障碍,()回顾进行重病谈话的最佳实践和具体方法,以及()提供克服障碍的解决方案以及实用建议,包括具体的语言和工具,以在透析人群中开展重病谈话。