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快速分子传染病诊断的实施:诊断与抗菌药物管理的作用

Implementation of Rapid Molecular Infectious Disease Diagnostics: the Role of Diagnostic and Antimicrobial Stewardship.

作者信息

Messacar Kevin, Parker Sarah K, Todd James K, Dominguez Samuel R

机构信息

Section of Hospital Medicine, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA

Section of Infectious Diseases, Department of Pediatrics, Children's Hospital Colorado-University of Colorado School of Medicine, Aurora, Colorado, USA.

出版信息

J Clin Microbiol. 2017 Mar;55(3):715-723. doi: 10.1128/JCM.02264-16. Epub 2016 Dec 28.

Abstract

New rapid molecular diagnostic technologies for infectious diseases enable expedited accurate microbiological diagnoses. However, diagnostic stewardship and antimicrobial stewardship are necessary to ensure that these technologies conserve, rather than consume, additional health care resources and optimally affect patient care. Diagnostic stewardship is needed to implement appropriate tests for the clinical setting and to direct testing toward appropriate patients. Antimicrobial stewardship is needed to ensure prompt appropriate clinical action to translate faster diagnostic test results in the laboratory into improved outcomes at the bedside. This minireview outlines the roles of diagnostic stewardship and antimicrobial stewardship in the implementation of rapid molecular infectious disease diagnostics.

摘要

用于传染病的新型快速分子诊断技术能够实现快速准确的微生物学诊断。然而,诊断管理和抗菌药物管理对于确保这些技术节省而非消耗额外的医疗资源并对患者护理产生最佳影响而言是必要的。需要进行诊断管理以针对临床环境实施适当的检测,并将检测导向合适的患者。需要进行抗菌药物管理以确保迅速采取适当的临床行动,将实验室中更快的诊断检测结果转化为床边更好的治疗效果。本综述概述了诊断管理和抗菌药物管理在实施快速分子传染病诊断中的作用。

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