Pham Luyen Dinh, Phung Nhat Huy Tran, Le Nguyen Tu Dang, Vo Trung Quang
Department of Pharmacy Administration, Faculty of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Clinicoecon Outcomes Res. 2016 Dec 16;9:1-8. doi: 10.2147/CEOR.S124023. eCollection 2017.
Dengue is a mosquito-borne viral illness with the world's fastest rate of infection. In 2014, Vietnam had recorded 43,000 cases in 53 provinces, with 28 deaths.
A 6-month cross-sectional study was conducted from September 2015 to March 2016 at Cu Chi General Hospital. Cost of illness in this study was estimated under the incidence-based approach from the societal perspective.
The average cost per case was US$139.3±$61.7. The average cost per child was higher than per adult, but not significant ($151.0±$63.5 and $132.7±$59.9, respectively; =0.068). Meanwhile, 50.2% of the total cost was contributed by the cost of hospital bed. According to the sensitivity analysis, if both the costs of the hospital bed and ultrasound were reduced by 10%, the total treatment cost of dengue fever would fall by 5% and 1.6%, respectively.
This study is expected to be the basis for investment-plan formulation and fund allocation for the treatment and prevention of dengue. In an attempt to examine the entire socioeconomic encumbrance caused by the dengue virus, a larger scale study targeting both dengue and dengue hemorrhagic fever needs to be conducted in several hospitals.
登革热是一种由蚊子传播的病毒性疾病，其感染率在全球范围内增长最快。2014年，越南53个省份共记录了43000例病例，其中28人死亡。
2015年9月至2016年3月，在古芝综合医院进行了一项为期6个月的横断面研究。本研究从社会角度采用基于发病率的方法估算疾病成本。
每例病例的平均成本为139.3美元±61.7美元。儿童的平均成本高于成人，但差异不显著（分别为151.0美元±63.5美元和132.7美元±59.9美元；P = 0.068）。同时，总成本的50.2%由住院床位成本构成。根据敏感性分析，如果住院床位和超声检查的成本均降低10%，登革热的总治疗成本将分别下降5%和1.6%。
本研究有望成为制定登革热治疗和预防投资计划及资金分配的依据。为了全面评估登革热病毒造成的社会经济负担，需要在多家医院开展针对登革热和登革出血热的更大规模研究。
