Institute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam.
Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Int J Environ Res Public Health. 2018 Jun 5;15(6):1174. doi: 10.3390/ijerph15061174.
Dengue fever (DF) outbreaks occur intermittently in Vietnam, and the most recent epidemic happened in 2017. However, attempts to measure the burden of DF in relation to the quality of life and the cost of treatment for patients during an epidemic period are constrained. This study explored the health-related quality of life (HRQOL) and the cost of illness among patients with dengue fever in Vietnam. A cross-sectional study was conducted in Bach Mai Hospital from September to November 2017. The EuroQol-5 dimensions-5 levels (EQ-5D-5L) was used to measure HRQOL. Cost-of illness was measured by collecting data about the direct medical cost, the non-medical cost, and the indirect cost. Among 225 patients, most of the participants experienced problems regarding mobility (62.3%), self-care (71.8%), usual activities (64.6%), and anxiety/depression (64.1%). The mean EQ-5D index was 0.66 (SD = 0.24). The median cost of illness for inpatient and outpatient groups were US $110.10 (IQR = US $4.40⁻1200.00) and US $36.10 (IQR = US $1.80⁻816.30), respectively. Indirect costs accounted for a major proportion in both groups. Lower-skilled workers and those with a higher severity of the disease had significantly lower HRQOL. Meanwhile, people who were inpatients, had comorbidities, had higher incomes, and who experienced a longer disease duration, had a higher cost of treatment. In conclusion, high costs and severe health deterioration, especially in psychological dimensions, were found in patients with DF in Vietnam. Strengthening primary health care services and communication campaigns are necessary to relieve the burden of diseases and could possibly contribute to effective DF control and prevention strategies.
登革热（DF）在越南间歇性爆发，最近一次疫情发生在 2017 年。然而，在疫情期间衡量 DF 负担与患者生活质量和治疗成本的尝试受到限制。本研究探讨了越南登革热患者的健康相关生活质量（HRQOL）和疾病经济负担。2017 年 9 月至 11 月，在白梅医院进行了一项横断面研究。使用欧洲五维健康量表 5 级（EQ-5D-5L）来衡量 HRQOL。通过收集直接医疗成本、非医疗成本和间接成本的数据来衡量疾病经济负担。在 225 名患者中，大多数参与者在行动能力（62.3%）、自理能力（71.8%）、日常活动（64.6%）和焦虑/抑郁（64.1%）方面存在问题。EQ-5D 指数的平均值为 0.66（SD=0.24）。住院和门诊组的疾病经济负担中位数分别为 110.10 美元（IQR=4.40-1200.00 美元）和 36.10 美元（IQR=1.80-816.30 美元）。间接成本在两组中占主要比例。低技能工人和病情较重的患者 HRQOL 明显较低。同时，住院患者、合并症患者、收入较高患者和疾病持续时间较长患者的治疗费用较高。总之，越南登革热患者的治疗费用较高，健康状况严重恶化，尤其是在心理维度。加强初级卫生保健服务和宣传活动是减轻疾病负担的必要措施，这可能有助于制定有效的登革热控制和预防策略。
