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肥胖青少年中的黑棘皮病:患病率、影响及管理挑战

Acanthosis nigricans in obese adolescents: prevalence, impact, and management challenges.

作者信息

Ng Hak Yung

机构信息

Department of Paediatrics and Adolescent Medicine, Tseung Kwan O Hospital, Tseung Kwan O, Hong Kong, China.

出版信息

Adolesc Health Med Ther. 2016 Dec 16;8:1-10. doi: 10.2147/AHMT.S103396. eCollection 2017.

Abstract

Obesity in adolescence is a public health priority because it usually tracks into adulthood, resulting in enormous medical and social costs. This underscores the importance of early identification and intervention. Acanthosis nigricans (AN) was once considered a rare paraneoplastic dermatosis, but is now frequently observed in obese adolescents. Current understanding suggests that it is associated with insulin resistance and has a unique role in secondary prevention. The purpose of this narrative review is to provide a comprehensive overview of AN in obese adolescents, covering its history, current knowledge on the condition, its clinical significance, management challenges, and the direction of future research.

摘要

青少年肥胖是公共卫生的重点问题,因为它通常会延续至成年期,导致巨大的医疗和社会成本。这凸显了早期识别和干预的重要性。黑棘皮病(AN)曾被认为是一种罕见的副肿瘤性皮肤病,但现在在肥胖青少年中经常可见。目前的认识表明,它与胰岛素抵抗有关,并且在二级预防中具有独特作用。本叙述性综述的目的是全面概述肥胖青少年中的黑棘皮病,涵盖其历史、对该病症的当前认识、其临床意义、管理挑战以及未来研究方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb61/5179206/9d40698c2abe/ahmt-8-001Fig1.jpg

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