肝移植术后即刻出现的高血糖症。

Hyperglycemia during the immediate period following liver transplantation.

作者信息

Werner K Tuesday, Mackey Patricia A, Castro Janna C, Carey Elizabeth J, Chakkera Harini A, Cook Curtiss B

机构信息

Division of Gastroenterology & Hepatology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA; Division of Gastroenterology & Hepatology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA.

Division of Endocrinology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA; Division of Endocrinology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA.

出版信息

Future Sci OA. 2016 Jan 27;2(1):FSO97. doi: 10.4155/fsoa-2015-0010. eCollection 2016 Mar.

DOI:10.4155/fsoa-2015-0010

PMID:28031946

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5138006/

Abstract

AIM

High blood glucose levels in the hospital are common among transplant recipients.

METHODS

Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM).

RESULTS

Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23% for every 5-year age increase (odds ratio: 1.23; 95% CI: 1.06-1.44; p = 0.007) and 51% for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95% CI: 1.23-1.95; p < 0.01).

CONCLUSION

Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients.

摘要

目的

移植受者在医院中血糖水平高很常见。

方法

回顾性分析，按移植前糖尿病（DM）诊断分层。

结果

346例患者中，96例有移植前DM（胰岛素治疗，n = 60；非胰岛素治疗，n = 36），250例没有。移植前DM患者住院期间平均血糖水平更高，高血糖和低血糖情况更多（均p < 0.01）。对于没有移植前DM的患者，出院时胰岛素需求随年龄每增加5岁增加23%（比值比：1.23；95%置信区间：1.06 - 1.44；p = 0.007），血糖测量值每高于180 mg/dl五个单位胰岛素需求增加51%（比值比：1.51；95%置信区间：1.23 - 1.95；p < 0.01）。