A Water-Soluble Fluorescent Probe for SO Derivatives in Aqueous Solution and Serum Based on Phenanthroimidazole Dye.

A water-soluble fluorescent SO derivatives probe PI-SO based on a phenanthroimidazole dye, and a sensitive SO recognition site, aldehyde was constructed. The probe PI-SO exhibits desirable properties such as high sensitivity, high selectivity and good water-solubility. Significantly, we have demonstrated that the probe PI-SO is suitable for rapidly fluorescence detecting of SO derivatives in aqueous solution and serum. The application of the novel probe PI-SO proved that it was not only a useful tool for the detection of SO derivatives in vitro, but also a potential assay for investigating the effects of SO derivatives, and demonstrating its value in practical applicationin of complex biological samples.