College of Materials and Chemical Engineering, Key laboratory of inorganic nonmetallic crystalline and energy conversion materials, China Three Gorges University, Yichang, 443002, People's Republic of China.
College of Biology and Pharmacy, China Three Gorges University, Yichang, 443002, People's Republic of China.
J Fluoresc. 2017 May;27(3):799-804. doi: 10.1007/s10895-016-2015-9. Epub 2016 Dec 28.
A water-soluble fluorescent SO derivatives probe PI-SO based on a phenanthroimidazole dye, and a sensitive SO recognition site, aldehyde was constructed. The probe PI-SO exhibits desirable properties such as high sensitivity, high selectivity and good water-solubility. Significantly, we have demonstrated that the probe PI-SO is suitable for rapidly fluorescence detecting of SO derivatives in aqueous solution and serum. The application of the novel probe PI-SO proved that it was not only a useful tool for the detection of SO derivatives in vitro, but also a potential assay for investigating the effects of SO derivatives, and demonstrating its value in practical applicationin of complex biological samples.
一种基于菲啰啉染料的水溶性荧光 SO 衍生物探针 PI-SO，并构建了一个灵敏的 SO 识别位点醛基。探针 PI-SO 表现出高灵敏度、高选择性和良好的水溶性等理想特性。值得注意的是，我们已经证明该探针 PI-SO 适用于在水溶液和血清中快速荧光检测 SO 衍生物。新型探针 PI-SO 的应用证明了它不仅是体外检测 SO 衍生物的有用工具，也是研究 SO 衍生物作用的潜在方法，并证明了其在复杂生物样品实际应用中的价值。
