Liu Yu, Li Kun, Xie Ke-Xin, Li Ling-Ling, Yu Kang-Kang, Wang Xin, Yu Xiao-Qi
Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, P. R. China.
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Chem Commun (Camb). 2016 Feb 25;52(16):3430-3. doi: 10.1039/c5cc10505f.
A novel water-soluble mitochondria-targeted ratiometric fluorescent probe (Cl-2) is presented. Cl-2 can respond selectively to SO2 derivatives within 1 min. Notably, Cl-2 can be used to monitor successfully the concentration change of endogenously generated SO2 derivatives in living cells.
本文报道了一种新型的水溶性线粒体靶向比率荧光探针(Cl-2)。Cl-2能够在1分钟内对二氧化硫衍生物做出选择性响应。值得注意的是,Cl-2可成功用于监测活细胞内源性生成的二氧化硫衍生物的浓度变化。