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一种用于比色和比率传感活细胞内源性生成的二氧化硫衍生物的水溶性快速响应线粒体靶向荧光探针。

A water-soluble and fast-response mitochondria-targeted fluorescent probe for colorimetric and ratiometric sensing of endogenously generated SO2 derivatives in living cells.

作者信息

Liu Yu, Li Kun, Xie Ke-Xin, Li Ling-Ling, Yu Kang-Kang, Wang Xin, Yu Xiao-Qi

机构信息

Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, P. R. China.

Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.

出版信息

Chem Commun (Camb). 2016 Feb 25;52(16):3430-3. doi: 10.1039/c5cc10505f.

Abstract

A novel water-soluble mitochondria-targeted ratiometric fluorescent probe (Cl-2) is presented. Cl-2 can respond selectively to SO2 derivatives within 1 min. Notably, Cl-2 can be used to monitor successfully the concentration change of endogenously generated SO2 derivatives in living cells.

摘要

本文报道了一种新型的水溶性线粒体靶向比率荧光探针(Cl-2)。Cl-2能够在1分钟内对二氧化硫衍生物做出选择性响应。值得注意的是,Cl-2可成功用于监测活细胞内源性生成的二氧化硫衍生物的浓度变化。

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