Kubik Mark, Barasch Nicholas, Choby Garret, Seethala Raja, Snyderman Carl
Department of Otolaryngology, Center for Cranial Base Surgery, University of Pittsburgh Medical Center, 200 Lothrop Street, EEI 521, Pittsburgh, PA, 15213, USA.
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Head Neck Pathol. 2017 Sep;11(3):333-337. doi: 10.1007/s12105-016-0774-x. Epub 2016 Dec 28.
The differential diagnosis for clear cell neoplasms of the sinonasal tract is wide but critical to understand. In this paper, we describe a case of renal cell-like adenocarcinoma (SNRCLA) presenting as a paranasal sinus mass with clear cell morphology. The relevant literature is reviewed and the workup for clear cell neoplasms described. SNRCLA is a rarely encountered low grade glandular malignancy of the paranasal sinuses. Despite its morphologic mimicry of renal cell carcinoma, SNRCLA demonstrates a seromucinous phenotype and is associated with a favorable prognosis and low recurrence rates after surgical resection.
鼻窦透明细胞肿瘤的鉴别诊断范围广泛,但理解起来至关重要。在本文中,我们描述了一例表现为鼻窦肿块且具有透明细胞形态的肾细胞样腺癌(SNRCLA)。回顾了相关文献并描述了透明细胞肿瘤的检查方法。SNRCLA是一种罕见的鼻窦低度腺性恶性肿瘤。尽管其形态学上类似于肾细胞癌,但SNRCLA表现出浆液黏液性表型,手术切除后预后良好且复发率低。