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重症气道狭窄手术期间体外生命支持的结果

Outcomes of Extracorporeal Life Support During Surgery for the Critical Airway Stenosis.

作者信息

Kim Seon Hee, Song Seunghwan, Kim Yeong Dae, I Hoseok, Cho Jeong Su, Ahn Hyo Yeong, Lee Jonggeun, Kim Do Hyung, Son Bong Soo

机构信息

From the *Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Biomedical Research Institute, Busan, Republic of Korea; and †Departments of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea.

出版信息

ASAIO J. 2017 Jan/Feb;63(1):99-103. doi: 10.1097/MAT.0000000000000458.

Abstract

Anesthetic management of critical airway stenosis is often very challenging. Extracorporeal membrane oxygenation (ECMO) may provide adequate respiratory support when conventional approaches fail. We report our experience of ECMO support for critical airway surgery. Between April 2012 and March 2015, nine patients underwent ECMO-supported airway operation. The reason for surgery was tracheal stenosis in nine patients, and tracheomalacia, tracheal tumor, and external tracheal compression by mediastinal mass in one patient each. Resection and end-to-end anastomosis was performed in four patients; the remainder underwent diverse procedures, including tracheoplasty, tracheal ballooning, tracheostomy, and debulking of mediastinal mass. Extracorporeal membrane oxygenation support was sufficient for gas exchange during surgery and six patients were successfully weaned off intraoperatively. The median time on ECMO was 2.42 hours (range: 14.43-216 hours). No ECMO-related complications occurred. The median intensive care unit stay, median hospital stay, and mean follow-up period were 2 days (range: 1-61 days), 33 days (range: 9-303 days), and 17.1 ± 10.8 months, respectively. The rate of freedom from reintervention was 71.4%; the mean survival rates over 1 and 2 years were 76.2% and 63.5%, respectively. Our experience indicates that ECMO is a feasible and safe method for critical airway surgery.

摘要

重症气道狭窄的麻醉管理通常极具挑战性。当传统方法失败时,体外膜肺氧合(ECMO)可提供足够的呼吸支持。我们报告了我们对重症气道手术进行ECMO支持的经验。2012年4月至2015年3月期间,9例患者接受了ECMO支持的气道手术。手术原因9例为气管狭窄,1例分别为气管软化、气管肿瘤和纵隔肿物压迫气管。4例患者进行了切除和端端吻合术;其余患者接受了包括气管成形术、气管球囊扩张术、气管切开术和纵隔肿物减容术等不同手术。体外膜肺氧合支持在手术期间足以进行气体交换,6例患者术中成功脱机。ECMO的中位时间为2.42小时(范围:14.43 - 216小时)。未发生与ECMO相关的并发症。重症监护病房的中位住院时间、中位住院时间和平均随访期分别为2天(范围:1 - 61天)、33天(范围:9 - 303天)和17.1±10.8个月。再次干预的无复发生存率为71.4%;1年和2年的平均生存率分别为76.2%和63.5%。我们的经验表明,ECMO是重症气道手术的一种可行且安全的方法。

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