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小儿重症气道手术围手术期的体外膜肺氧合支持

Perioperative extracorporeal membrane oxygenation support for critical pediatric airway surgery.

作者信息

Huang Shu-Chien, Wu En-Ting, Chi Nai-Hsin, Chiu Shuenn-Nan, Huang Pei-Ming, Chen Yih-Sharng, Lee Yung-Chie, Ko Wen-Je

机构信息

Department of Surgery, National Taiwan University Hospital, 7th Chung-Shan South Road, Taipei, 100, Taiwan.

出版信息

Eur J Pediatr. 2007 Nov;166(11):1129-33. doi: 10.1007/s00431-006-0390-y. Epub 2007 Jan 5.

Abstract

Extracorporeal membrane oxygenation (ECMO) has been used for cardiopulmonary support in neonates, infants, and adults. We report the application of ECMO for critical airway surgery when mechanical ventilation cannot provide adequate gas exchange. Three pediatric patients underwent emergency ECMO establishment because of hypercapnia that could not be managed by conventional mechanical ventilation. The pathology included: (1) left pulmonary artery sling with long-segment tracheal stenosis; (2) absence of the right intermediate bronchus and abnormal origin of the right lower bronchus arising from the left main bronchus; (3) right-lung agenesis with long-segment tracheobronchial stenosis. Venoarterial ECMO was established. Before ECMO, the arterial pH values were 7.28, 7.0, and 7.08, and the PaCO2 values were 111.8, 112.0, and 208.7 mmHg for each patient, respectively. After ECMO support, respiratory acidosis was reversed. The patients then underwent surgical intervention. The surgical procedures included: (1) slide tracheoplasty and reimplantation of the left pulmonary artery; (2) resection of the stenotic tracheal segment and reconstruction of the bronchial tree; (3) tracheal dilatation and stent implantation. The ECMO durations were 11, 5, and 16 h, respectively. All patients were successfully weaned off ECMO without complications. In conclusion, ECMO provided adequate ventilation support for patients undergoing critical tracheobronchial reconstruction when conventional mechanical ventilation could not maintain adequate gas exchange.

摘要

体外膜肺氧合(ECMO)已用于新生儿、婴儿及成人的心肺支持。我们报告在机械通气无法提供充足气体交换时,ECMO在危急气道手术中的应用。3例儿科患者因常规机械通气无法处理的高碳酸血症而接受紧急ECMO建立。病理情况包括:(1)左肺动脉吊带合并长段气管狭窄;(2)右中间支气管缺如,右下支气管起源异常,起自左主支气管;(3)右肺不发育合并长段气管支气管狭窄。建立了静脉-动脉ECMO。在ECMO之前,各患者的动脉pH值分别为7.28、7.0和7.08,PaCO2值分别为111.8、112.0和208.7 mmHg。在ECMO支持后,呼吸性酸中毒得到纠正。然后患者接受手术干预。手术操作包括:(1)滑动气管成形术及左肺动脉再植术;(2)切除狭窄气管段并重建支气管树;(3)气管扩张及支架植入。ECMO持续时间分别为11、5和16小时。所有患者均成功撤离ECMO,无并发症发生。总之,当常规机械通气无法维持充足气体交换时,ECMO为接受危急气管支气管重建的患者提供了充足的通气支持。

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