Nakamura Tomoko, Keino Hiroshi, Okada Annabelle A
Department of Ophthalmology, Kyorin University School of Medicine, Mitaka, Japan.
Department of Ophthalmology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Retin Cases Brief Rep. 2018;12(4):375-378. doi: 10.1097/ICB.0000000000000510.
To report a case of new-onset Vogt-Koyanagi-Harada disease treated with sub-Tenon injection of triamcinolone acetonide in a 16-week pregnant patient.
Review of clinical records.
A 33-year-old woman in her 16th week of pregnancy presented with bilateral serous retinal detachments associated with anterior chamber inflammation. Enhanced depth imaging optical coherence topography showed marked choroidal thickening. Headache and tinnitus developed 3 days later. The patient was diagnosed with incomplete Vogt-Koyanagi-Harada disease and treated with bilateral sub-Tenon triamcinolone acetonide injections. Within 2 weeks, the serous retinal detachments completely resolved with decreased choroidal thickness in both eyes. No recurrence of inflammation or choroidal thickening was noted over a follow-up of 13 months. The patient delivered a healthy baby at 41 weeks of pregnancy.
Sub-Tenon triamcinolone acetonide injection may be an effective and safe treatment in pregnant women with new-onset Vogt-Koyanagi-Harada disease.
报告1例16周妊娠的新发Vogt-小柳原田病患者，采用球后注射曲安奈德治疗。
回顾临床记录。
一名妊娠16周的33岁女性出现双侧浆液性视网膜脱离并伴有前房炎症。增强深度成像光学相干断层扫描显示脉络膜明显增厚。3天后出现头痛和耳鸣。该患者被诊断为不完全性Vogt-小柳原田病，并接受了双侧球后注射曲安奈德治疗。2周内，浆液性视网膜脱离完全消退，双眼脉络膜厚度降低。在13个月的随访中未发现炎症复发或脉络膜增厚。患者在妊娠41周时分娩了一名健康婴儿。
球后注射曲安奈德可能是治疗新发Vogt-小柳原田病孕妇的一种有效且安全的方法。
