MMWR Morb Mortal Wkly Rep. 2016 Dec 30;65(50-51):1430-1433. doi: 10.15585/mmwr.mm655051a3.
In April 2016, PulseNet, the national molecular subtyping network for foodborne disease surveillance, detected a multistate cluster of Salmonella enterica serotype Oslo infections with an indistinguishable pulsed-field gel electrophoresis (PFGE) pattern (XbaI PFGE pattern OSLX01.0090).* This PFGE pattern was new in the database; no previous infections or outbreaks have been identified. CDC, state and local health and agriculture departments and laboratories, and the Food and Drug Administration (FDA) conducted epidemiologic, traceback, and laboratory investigations to identify the source of this outbreak. A total of 14 patients in eight states were identified, with illness onsets occurring during March 21-April 9, 2016. Whole genome sequencing, a highly discriminating subtyping method, was used to further characterize PFGE pattern OSLX01.0090 isolates. Epidemiologic evidence indicates Persian cucumbers as the source of Salmonella Oslo infections in this outbreak. This is the fourth identified multistate outbreak of salmonellosis associated with cucumbers since 2013. Further research is needed to understand the mechanism and factors that contribute to contamination of cucumbers during growth, harvesting, and processing to prevent future outbreaks.
2016 年 4 月,脉冲场凝胶电泳(PFGE)图谱完全一致的食源性疾病监测国家分子分型网络 PulseNet 检测到了一起由肠炎沙门氏菌血清型奥斯陆引起的多州感染集群。*这种 PFGE 图谱在数据库中是新的;此前未发现任何感染或暴发情况。美国疾病控制与预防中心(CDC)、州和地方卫生与农业部门和实验室以及食品和药物管理局(FDA)开展了流行病学、溯源和实验室调查,以确定此次暴发的源头。共确定了 8 个州的 14 名患者,发病时间为 2016 年 3 月 21 日至 4 月 9 日。全基因组测序是一种高度区分的分型方法,用于进一步描述 PFGE 图谱 OSLX01.0090 分离株。流行病学证据表明,波斯黄瓜是此次暴发中肠炎沙门氏菌感染的源头。这是自 2013 年以来第四起与黄瓜有关的沙门氏菌病多州暴发。需要进一步研究以了解导致黄瓜在生长、收获和加工过程中受到污染的机制和因素,以防止未来的暴发。