Mapp C E, Boschetto P, Picotti G, De Marzo N, Fabbri L M
Institute of Occupational Medicine, University of Padova, Italy.
Eur Respir J Suppl. 1989 Jun;6:566s-567s.
Anti-inflammatory steroids are the principal agents for the treatment of asthma. Systemic corticosteroids are recommended for the treatment of acute episodes of asthma, whereas inhaled steroids should be used in the long-term prophylaxis of asthma. Because of their side-effects, there is a need for additional research and development of steroids without systemic activity, and/or other anti-inflammatory agents for use in the long-term prophylaxis of asthma.
抗炎类固醇是治疗哮喘的主要药物。全身用皮质类固醇推荐用于治疗哮喘急性发作,而吸入性类固醇应用于哮喘的长期预防。由于其副作用,需要进一步研发无全身活性的类固醇和/或其他用于哮喘长期预防的抗炎药物。