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病态肥胖患者的经皮血管内动脉瘤修复术

Percutaneous endovascular aneurysm repair in morbidly obese patients.

作者信息

Chin Jason A, Skrip Laura, Sumpio Bauer E, Cardella Jonathan A, Indes Jeffrey E, Sarac Timur P, Dardik Alan, Ochoa Chaar Cassius I

机构信息

Section of Vascular Surgery, Yale University School of Medicine, New Haven, Conn.

Yale School of Public Health, New Haven, Conn.

出版信息

J Vasc Surg. 2017 Mar;65(3):643-650.e1. doi: 10.1016/j.jvs.2016.06.115. Epub 2016 Dec 27.

Abstract

OBJECTIVE

Endovascular aneurysm repair (EVAR) with percutaneous femoral access (PEVAR) has several potential advantages. Morbidly obese (MO) patients present unique anatomical challenges and have not been specifically studied. This study examines the trends in the use of PEVAR and its surgical outcomes compared with open femoral cutdown (CEVAR) in MO patients.

METHODS

The American College of Surgeons National Surgical Quality Improvement Program files for the years 2005 to 2013 were reviewed. The study included all MO patients (body mass index [BMI] ≥40 kg/m) undergoing EVAR. Patients were categorized as having CEVAR if they had any one of 11 selected Current Procedural Terminology (American Medical Association, Chicago, Ill) codes describing an open femoral procedure. The PEVAR group included any remaining patients who had only codes for EVAR and endovascular procedures. Linear correlation was used to evaluate temporal trends in the use of PEVAR among MO patients. Baseline comorbidities and surgical outcomes were compared between the PEVAR and CEVAR groups using χ tests or t-tests.

RESULTS

There were 833 MO patients (470 CEVAR and 363 PEVAR) constituting 3.0% of all patients undergoing EVAR. The use of PEVAR in MO patients significantly increased from 27.3% of total EVARs in the years 2005 to 2006 to 48.6% in 2013 (P = .039). The two groups had similar baseline characteristics, including age, BMI, comorbidities, and emergency procedures, except for history of severe chronic obstructive pulmonary disease (29.6% CEVAR vs 22.6% PEVAR; P = .024). PEVAR patients had shorter duration of anesthesia (244 vs 260 minutes; P = .048) and shorter total operation time (158 vs 174 minutes; P = .002). PEVAR patients had significantly decreased wound complications (5.5% vs 9.4%; P = .039). There was a trend towards PEVAR patients being more likely to be discharged home than to a facility (93.6% vs 87.8%; P = .060). There was no difference in any other complication or mortality. A subgroup analysis of 109 superobese patients with BMI ≥50 kg/mg (59 CEVAR and 50 PEVAR) demonstrated no significant differences in outcomes between groups.

CONCLUSIONS

PEVAR is increasingly used in MO patients and decreases operating time and rates of wound infection compared with CEVAR. The advantages of PEVAR seem to be lost in the superobese patients.

摘要

目的

经皮股动脉入路的血管内动脉瘤修复术(PEVAR)具有若干潜在优势。病态肥胖(MO)患者存在独特的解剖学挑战,且尚未得到专门研究。本研究探讨了MO患者中PEVAR的使用趋势及其与开放式股动脉切开术(CEVAR)相比的手术结果。

方法

回顾了美国外科医师学会国家外科质量改进计划2005年至2013年的档案。该研究纳入了所有接受血管内动脉瘤修复术的MO患者(体重指数[BMI]≥40kg/m²)。如果患者有11个选定的当前手术操作术语(美国医学协会,伊利诺伊州芝加哥)代码中的任何一个描述开放式股动脉手术,则将其归类为接受CEVAR。PEVAR组包括仅具有血管内动脉瘤修复术和血管内手术代码的其余患者。使用线性相关性评估MO患者中PEVAR使用的时间趋势。使用χ²检验或t检验比较PEVAR组和CEVAR组之间的基线合并症和手术结果。

结果

有833例MO患者(470例CEVAR和363例PEVAR),占所有接受血管内动脉瘤修复术患者的3.0%。MO患者中PEVAR的使用从2005年至2006年占血管内动脉瘤修复术总数的27.3%显著增加到2013年的48.6%(P = 0.039)。除了严重慢性阻塞性肺疾病史外,两组具有相似的基线特征,包括年龄、BMI、合并症和急诊手术(29.6%的CEVAR患者 vs 22.6%的PEVAR患者;P = 0.024)。PEVAR患者的麻醉持续时间较短(244分钟 vs 260分钟;P = 0.048),总手术时间较短(158分钟 vs 174分钟;P = 0.002)。PEVAR患者的伤口并发症显著减少(5.5% vs 9.4%;P = 0.039)。PEVAR患者比CEVAR患者更有可能出院回家(93.6% vs 87.8%;P = 0.060)。在任何其他并发症或死亡率方面没有差异。对109例BMI≥50kg/m²的极度肥胖患者(59例CEVAR和50例PEVAR)进行的亚组分析表明,两组之间的结果没有显著差异。

结论

与CEVAR相比,PEVAR在MO患者中的使用越来越多,并且减少了手术时间和伤口感染率。在极度肥胖患者中,PEVAR的优势似乎消失了。

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