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Staining the target: CD37 expression in lymphomas.

作者信息

Bertoni Francesco, Stathis Anastasios

机构信息

INSTITUTE OF ONCOLOGY RESEARCH.

ONCOLOGY INSTITUTE OF SOUTHERN SWITZERLAND.

出版信息

Blood. 2016 Dec 29;128(26):3022-3023. doi: 10.1182/blood-2016-11-748137.

DOI:10.1182/blood-2016-11-748137
PMID:28034866
Abstract
摘要

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PI3Kδ activation, IL-6 overexpression, and CD37 loss cause resistance to naratuximab emtansine in lymphomas.PI3Kδ激活、白细胞介素-6过表达和CD37缺失导致淋巴瘤对纳拉妥昔单抗恩坦辛耐药。
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CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia.
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