Sweet R L, Landers D V, Schachter J, Crombleholme W R
Department of Obstetrics and Gynecology, University of California, San Francisco.
Suppl Int J Gynecol Obstet. 1989;2:13-9; discussion 47-8. doi: 10.1016/0020-7292(89)90087-8.
Acute pelvic inflammatory disease is associated with significant adverse reproductive sequelae. To prevent these serious sequelae, treatment regimens must cover the major etiologic agents which are Neisseria gonorrhoeae, Chlamydia trachomatis, and mixed anaerobic-aerobic bacteria. This report concerns the prospective evaluation of the efficacy of the combination of sulbactam with ampicillin in patients hospitalized with acute pelvic inflammatory disease. Clinical cure was noted in 33 (94%) of 35 patients and post-treatment cultures demonstrated eradication of N. gonorrhoeae and C. trachomatis in all cases.
