Fimognari Carmela
Department for Life Quality Studies, Alma Mater Studiorum-University of Bologna, Corso d'Augusto 237, Rimini 47921, Italy.
Toxins (Basel). 2016 Dec 28;9(1):12. doi: 10.3390/toxins9010012.
The role of many phytochemicals in the modulation of the carcinogenesis process has been well documented by combining in vitro and animal studies, as well as epidemiological evidence. When acting in synergy, phytochemicals exert potential anti-cancer properties, and much progress has been made in defining their many biological activities at the molecular level. However, an interesting feature in the field of phytochemicals and cancer is the role of some phytochemicals in promoting cancer development. This Special Issue of Toxins aims to provide a comprehensive look at the contribution of dietary and non-dietary phytochemicals to cancer development and at the molecular mechanisms by which phytochemicals inhibit or promote cancer.[...].
通过结合体外研究、动物研究以及流行病学证据,许多植物化学物质在癌症发生过程调节中的作用已得到充分证明。当协同作用时,植物化学物质发挥潜在的抗癌特性,并且在分子水平上确定它们的多种生物活性方面已经取得了很大进展。然而,植物化学物质与癌症领域一个有趣的特点是一些植物化学物质在促进癌症发展中的作用。本期《毒素》特刊旨在全面探讨膳食和非膳食植物化学物质对癌症发展的贡献以及植物化学物质抑制或促进癌症的分子机制。[……]