Oh Jisun, Hlatky Lynn, Jeong Yong-Seob, Kim Dohoon
School of Food Science and Biotechnology (BK21 Plus), Kyungpook National University, Daegu 41566, Korea.
Center of Cancer Systems Biology, Tufts University School of Medicine, Boston, MA 02135, USA.
Toxins (Basel). 2016 Jun 30;8(7):199. doi: 10.3390/toxins8070199.
Understanding how to target cancer stem cells (CSCs) may provide helpful insights for the development of therapeutic or preventive strategies against cancers. Dietary phytochemicals with anticancer properties are promising candidates and have selective impact on CSCs. This review summarizes the influence of phytochemicals on heterogeneous cancer cell populations as well as on specific targeting of CSCs.
了解如何靶向癌症干细胞(CSCs)可能为开发抗癌治疗或预防策略提供有益的见解。具有抗癌特性的膳食植物化学物质是很有前景的候选物,并且对癌症干细胞有选择性影响。本综述总结了植物化学物质对异质性癌细胞群体以及对癌症干细胞特异性靶向的影响。