Polo O, Brissaud L, Fraga J, Déjean Y, Billiard M
Department of Physiology, University of Turku, Finland.
Arch Otolaryngol Head Neck Surg. 1989 Nov;115(11):1350-4. doi: 10.1001/archotol.1989.01860350084020.
Uvulopalatopharyngoplasty is the treatment of choice for selected patients with obstructive sleep apnea, although the response to surgery is variable. We measured, in addition to obstructive apnea, the frequency of sleep-related partial upper airway obstruction in 11 patients with the obstructive sleep apnea syndrome both before and after uvulopalatopharyngoplasty. Partial obstruction was detected indirectly by recording the secondary hemodynamic changes and respiratory stimulation with the static charge sensitive bed. The frequency of obstructive apnea episodes was reduced from 56.3% to 18.4% by the operation, while the episodes of increased respiratory resistance rose from 3.6% to 20.4%. The various breathing anomalies decreased significantly, although they were still present during 75.6% of the recording time. The results suggest that uvulopalatopharyngoplasty substantially reduces the frequency of obstructive apnea, some of which persists as partial obstruction. The persistent partial obstruction may be the key factor contributing to further pharyngeal narrowing and a recurrence of obstructive sleep apnea syndrome.
悬雍垂腭咽成形术是特定阻塞性睡眠呼吸暂停患者的首选治疗方法,尽管手术效果因人而异。我们对11例阻塞性睡眠呼吸暂停综合征患者在悬雍垂腭咽成形术前后,除了测量阻塞性呼吸暂停外,还测量了与睡眠相关的部分上气道阻塞的频率。通过使用静电敏感床记录继发性血流动力学变化和呼吸刺激来间接检测部分阻塞。手术使阻塞性呼吸暂停发作的频率从56.3%降至18.4%,而呼吸阻力增加的发作从3.6%升至20.4%。各种呼吸异常显著减少,尽管在记录时间的75.6%期间仍存在。结果表明,悬雍垂腭咽成形术可大幅降低阻塞性呼吸暂停的频率,其中一些会持续存在为部分阻塞。持续的部分阻塞可能是导致进一步咽部狭窄和阻塞性睡眠呼吸暂停综合征复发的关键因素。