Scarazatti E, Borroni A, Melloni C F
Boll Soc Ital Biol Sper. 1989 Aug;65(8):767-74.
The electrophoresis of serum isoenzymes in cancer pathology at different stages has enabled us to recognise for LDH4 and LDH5, characteristics of sensitivity in all stages, with positivity greater than 60% in the advanced and multiply metastasized stages or with interference from other pathologies; to reveal portions pathologically heavy like FAST (46%); to reveal atypical bands (BB and MIT), as well as the values for normal or really low enzymatic activity. Through the elevated sensitivity and the high percentage of positivity, the isoenzymes LDH4 and LDH5 can be considered tumour markers and superior in validity to the conventional markers.
不同阶段癌症病理学中血清同工酶的电泳分析使我们能够识别出乳酸脱氢酶4（LDH4）和乳酸脱氢酶5（LDH5）在各阶段的敏感性特征，在晚期和多发转移阶段其阳性率大于60%，或存在其他病理干扰；揭示如FAST（46%）等病理严重部分；揭示非典型条带（BB和MIT）以及正常或极低酶活性的值。通过高敏感性和高阳性率，LDH4和LDH5同工酶可被视为肿瘤标志物，其有效性优于传统标志物。
