Hajsadeghi Shokoufeh, Firouzi Ata, Bahadoran Pouria, Hassanzadeh Morteza
Department of Cardiology, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Shahid Rajaei Heart Hospital, Iran University of Medical Sciences, Tehran, Iran.
Indian Heart J. 2016 Dec;68 Suppl 3(Suppl 3):S5-S9. doi: 10.1016/j.ihj.2016.10.011. Epub 2016 Nov 5.
Recently, the value of various structural body components have been proposed for predicting cardio-metabolic risk. The present study aimed to assess the wrist circumference (WrC) as an alternative measure for differentiating patients with CAD and METs from those without CAD and METs.
We studied 228 consecutive subjects who underwent coronary angiography. Those with and without evidence of coronary artery involvement at angiography were considered as the coronary artery disease (CAD) group (n=139) and the non-CAD group (n=89), respectively. WrC was measured; and metabolic syndrome (METs) was defined according to the modified National Cholesterol Education Program Adult Treatment Panel III criteria.
WrC was significantly higher in CAD compared to non-CAD patients (17.85±1.29mm vs 17.43±1.29mm, P=0.017). The overall prevalence of METs was significantly different between the CAD and non-CAD subjects (74.3% vs 58.8%, P=0.016). Although there was a tendency for association, no statistically significant association between the mean of the WrC and the severity of CAD was found (P=0.065). WrC had a weak positive correlation with triglyceride (r=0.172, P=0.011) and cholesterol (r=0.141, P=0.038) level and a weak negative association with high-density lipoprotein level (r=-0.279, P<0.001). In multivariate logistic regression models, WrC could predict neither presence of CAD nor METs.
Although correlated with METs-type lipid profile, WrC may not be a valuable index for predicting the presence of CAD or METs.
最近，有人提出各种身体结构成分的值可用于预测心血管代谢风险。本研究旨在评估腕围（WrC）作为区分患有冠心病和代谢综合征（METs）的患者与未患冠心病和METs的患者的替代指标。
我们研究了228例连续接受冠状动脉造影的受试者。冠状动脉造影时有和无冠状动脉受累证据的受试者分别被视为冠心病（CAD）组（n = 139）和非CAD组（n = 89）。测量了WrC；并根据修改后的美国国家胆固醇教育计划成人治疗小组III标准定义了代谢综合征（METs）。
CAD患者的WrC显著高于非CAD患者（17.85±1.29mm对17.43±1.29mm，P = 0.017）。CAD和非CAD受试者之间METs的总体患病率有显著差异（74.3%对58.8%，P = 0.016）。虽然有相关性趋势，但未发现WrC平均值与CAD严重程度之间存在统计学显著关联（P = 0.065）。WrC与甘油三酯（r = 0.172，P = 0.011）和胆固醇（r = 0.141，P = 0.038）水平呈弱正相关，与高密度脂蛋白水平呈弱负相关（r = -0.279，P < 0.001）。在多变量逻辑回归模型中，WrC既不能预测CAD的存在，也不能预测METs的存在。
虽然WrC与METs型血脂谱相关，但它可能不是预测CAD或METs存在的有价值指标。
