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腹腔镜左侧结直肠癌切除术后预防内疝和盆腔粘连:纤维蛋白封闭剂的作用

Prevention of internal hernias and pelvic adhesions following laparoscopic left-sided colorectal resection: the role of fibrin sealant.

作者信息

Angelini Pierluigi, Sciuto Antonio, Cuccurullo Diego, Pirozzi Felice, Reggio Stefano, Corcione Francesco

机构信息

Department of Laparoscopic and Robotic Surgery, ''Azienda Ospedaliera dei Colli'' - Monaldi Hospital, Via Leonardo Bianchi s.n.c, 80131, Naples, NA, Italy.

出版信息

Surg Endosc. 2017 Jul;31(7):3048-3055. doi: 10.1007/s00464-016-5328-5. Epub 2016 Dec 30.

Abstract

BACKGROUND

Laparoscopy has increasingly become the standard of care for patients who undergo colorectal surgery for both benign and malignant diseases. This growing experience has also resulted in more reports of postoperative complications from the minimally invasive approach to primary colorectal resection. Small bowel obstruction from internal hernias and pre-sacral adhesions is an uncommon but not negligible complication. However, there is little literature specific to this topic with recommendations for different methods to prevent it. We report our original technique of closing the mesenteric defect and covering the pre-sacral fascia by using fibrin sealant to prevent this complication.

METHODS

From January 2005 to December 2014, a total of 1079 patients underwent elective laparoscopic left colorectal resection (left hemicolectomy or anterior rectal resection) in our department. In the first 298 procedures, the mesenteric defect was left open, while in the following 781 procedures, it was closed using fibrin sealant with the aim of preventing postoperative small bowel obstruction.

RESULTS

Among the first 298 patients, three (1%) required reoperation for small bowel obstruction due to internal hernia (0.33%) or critical pre-sacral adhesions (0.66%). These complications did not occur in the subsequent series in which all 781 patients were treated with fibrin sealant prophylactic closure of the mesenteric defect.

CONCLUSION

In our experience, fibrin sealant closure of the mesenteric defect has demonstrated to be safe and effective in preventing postoperative small bowel obstruction that remains a complication both in open and in laparoscopic colorectal surgeries.

摘要

背景

对于因良性和恶性疾病接受结直肠手术的患者,腹腔镜检查已日益成为标准的治疗方法。随着这方面经验的不断积累,也有更多关于原发性结直肠切除微创方法术后并发症的报道。内疝和骶前粘连导致的小肠梗阻是一种少见但不可忽视的并发症。然而,针对该主题且有不同预防方法建议的文献很少。我们报告了一种通过使用纤维蛋白胶封闭肠系膜缺损并覆盖骶前筋膜来预防这种并发症的原创技术。

方法

2005年1月至2014年12月,我院共有1079例患者接受了选择性腹腔镜左半结肠切除术(左半结肠切除术或直肠前切除术)。在前298例手术中,肠系膜缺损未予处理,而在随后的781例手术中,为预防术后小肠梗阻,使用纤维蛋白胶封闭了肠系膜缺损。

结果

在前298例患者中,有3例(1%)因内疝(0.33%)或严重骶前粘连(0.66%)导致小肠梗阻而需要再次手术。在随后的系列病例中,所有781例患者均采用纤维蛋白胶预防性封闭肠系膜缺损,未发生这些并发症。

结论

根据我们的经验,纤维蛋白胶封闭肠系膜缺损已证明在预防术后小肠梗阻方面是安全有效的,而小肠梗阻在开放和腹腔镜结直肠手术中均是一种并发症。

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