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组件分离技术对复杂开放性腹疝修补术(OVHR)患者生活质量(QOL)和手术结果的影响。

The effect of component separation technique on quality of life (QOL) and surgical outcomes in complex open ventral hernia repair (OVHR).

机构信息

Division of Gastrointestinal and Minimally Invasive Surgery, Department of Surgery, Carolinas Medical Center, 1025 Morehead Medical Drive, Suite 300, Charlotte, NC, 28204, USA.

出版信息

Surg Endosc. 2017 Sep;31(9):3539-3546. doi: 10.1007/s00464-016-5382-z. Epub 2016 Dec 30.

Abstract

INTRODUCTION

Outcomes following OVHR may be affected by type of component separation. In this study, outcomes including QOL of patients undergoing OVHR were evaluated based on the utilization of transversus abdominis release (TAR), posterior rectus sheath release (PRSR) alone or in combination with external oblique release (EOR + PRSR).

METHODS

A prospective, single-institution study following open ventral hernia repair involving component separation was performed from May 2005 to April 2015. Self-reported QOL outcomes were obtained preoperatively and at 1, 6 and 12 months postoperatively using the Carolinas Comfort Scale (CCS). A CCS of 2 (mild but bothersome discomfort) or greater was considered symptomatic. Comorbidities, complications, outcomes and CCS scores were reviewed. Univariate group comparisons were performed using Chi-square and Wilcoxon two-sample tests with statistical significance set at p < 0.05.

RESULTS

During the study period, 292 OVHRs with CST met inclusion criteria. Single-sided, different releases on opposite sides, etc., were eliminated. Demographics included: average age-57.9 ± 11.9 years, BMI-34.0 ± 7.9 kgm, 53.2% female, 69% at least one prior hernia repair and average defect size-291.2 ± 236.2 cm. Preoperative discomfort (82 vs. 75 vs. 79%, p = 0.77) and movement limitation (94 vs. 70 vs. 78%, p = 0.1) in TAR, PRSR and EOR + PRSR were similar. Average follow-up was 16.4 months. At 1, 6 and 12 months postoperatively, there was no difference in reported CCS pain scores, movement limitation or mesh sensation among the groups (p > 0.05). Comparing OVHR patients outcomes by CST type, TAR was associated with decreased wound infections compared to others (3.2 vs. 16.1 vs. 20%, p = 0.07) while recurrence rates were increased in EOR + PRSR compared to TAR and PRSR alone(8.4 vs. 3 vs. 1.8%, p = 0.03). Eighty percent of recurrences had a biologic mesh secondary to contaminated field during hernia repair. The other two recurrences were one which occurred superior to the mesh at a suture site and one who developed a wound infection postoperatively. Mesh infection rates were low (0 vs. 1.5 vs. 2.6%, p > 0.05) even including contaminated cases (0 vs. 2 vs. 3.6%, p > 0.05) and were statistically equivalent among all three techniques.

CONCLUSION

While QOL is not impacted by type of component separation on short- or long-term follow-up, the TAR may provide benefits such as decreased wound infection rates. Overall QOL had a significant improvement from preoperative regardless of type of component separation. When controlling for field contamination, there were no differences in recurrence or infection.

摘要

简介

OVHR 后的结果可能受到分离组件类型的影响。在这项研究中,根据腹横肌释放(TAR)、腹直肌鞘后释放(PRSR)或联合外侧斜肌释放(EOR+PRSR)的使用情况,评估了接受 OVHR 的患者的生活质量(QOL)等结果。

方法

对 2005 年 5 月至 2015 年 4 月期间行开放式腹疝修补术伴组件分离的前瞻性单机构研究进行了评估。使用卡罗莱纳舒适度量表(CCS)在术前和术后 1、6 和 12 个月获得自我报告的 QOL 结果。CCS 为 2(轻度但令人不适)或更高被认为有症状。回顾了合并症、并发症、结果和 CCS 评分。使用卡方检验和 Wilcoxon 两样本检验进行单变量组比较,统计学意义设定为 p<0.05。

结果

在研究期间,符合 CST 的 292 例 OVHR 符合纳入标准。排除了单侧、对侧不同释放等情况。人口统计学包括:平均年龄 57.9±11.9 岁,BMI 34.0±7.9kgm,53.2%女性,69%至少有一次疝修补术,平均缺损大小 291.2±236.2cm。TAR、PRSR 和 EOR+PRSR 组术前不适(82%比 75%比 79%,p=0.77)和运动受限(94%比 70%比 78%,p=0.1)相似。平均随访时间为 16.4 个月。术后 1、6 和 12 个月,三组患者报告的 CCS 疼痛评分、运动受限或网片感觉无差异(p>0.05)。比较 CST 类型的 OVHR 患者结果,与其他类型相比,TAR 与减少伤口感染相关(3.2%比 16.1%比 20%,p=0.07),而 EOR+PRSR 与 TAR 和 PRSR 相比,复发率增加(8.4%比 3%比 1.8%,p=0.03)。80%的复发与疝修补术中污染区域的生物网片有关。另外两次复发中有一次发生在网片上方的缝合部位,另一次发生在术后伤口感染。网片感染率较低(0 比 1.5 比 2.6%,p>0.05),甚至包括污染病例(0 比 2 比 3.6%,p>0.05),在所有三种技术中统计学上没有差异。

结论

尽管短期或长期随访时 QOL 不受组件分离类型的影响,但 TAR 可能会降低伤口感染率等。无论组件分离类型如何,总体 QOL 均有显著改善。当控制污染区域时,复发或感染无差异。

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