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指南在手术决策中的作用:肝细胞癌范例

The effect of Guidelines in surgical decision making: The paradigm of hepatocellular carcinoma.

作者信息

Moris Demetrios, Vernadakis Spyridon, Papalampros Alexandros, Petrou Athanasios, Dimitroulis Dimitrios, Spartalis Eleftherios, Felekouras Evangelos, Fung John J

机构信息

Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

J BUON. 2016 Nov-Dec;21(6):1332-1336.

PMID:28039690
Abstract

It is not inconceivable to envision surgeons, offering extended liver resection in patients beyond the Barcelona Clinic Liver Cancer (BCLC) staging system criteria with intermediate/advanced hepatocellular carcinoma (HCC), to be found negligent since extensive liver resection is correlated with increased morbidity compared to conservative or palliative treatment. Given that no other classification system than BCLC has been adopted widely for HCC staging and treatment, a revision of the BCLC algorithm and clinical guidelines should be tailored using new molecular and clinical treatment algorithms, as well as including patient's preferences.

摘要

可以想象,对于超出巴塞罗那临床肝癌(BCLC)分期系统标准的中/晚期肝细胞癌(HCC)患者进行扩大肝切除术的外科医生,可能会被认定存在过失,因为与保守或姑息治疗相比,扩大肝切除术与更高的发病率相关。鉴于除BCLC外没有其他分类系统被广泛用于HCC分期和治疗,BCLC算法和临床指南的修订应根据新的分子和临床治疗算法进行调整,并纳入患者的偏好。

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