Relationships of linear and nonlinear ultrasound parameters with porosity and trabecular spacing in trabecular-bone-mimicking phantoms.

The speed of sound (SOS), the normalized broadband ultrasound attenuation (nBUA), and the nonlinear parameter (B/A) were measured in 18 trabecular-bone-mimicking phantoms consisting of water-saturated aluminum foams. The strong slow wave and the very weak fast wave were consistently observed in the signals transmitted through all of the phantoms. It was found that the SOS increased as the porosity and the trabecular spacing increased. In contrast, both the nBUA and the B/A showed opposite dependences on the porosity and the trabecular spacing. All three ultrasound parameters exhibited high correlation coefficients with the porosity and the trabecular spacing.