肾母细胞瘤转移至阴道：一例报告

Wilms Tumor With Metastasis to the Vagina: A Case Report.

作者信息

Howe Adam S, Morganstern Bradley A, Appelbaum Heather, Mehta Sandeep, Palmer Lane S

机构信息

Division of Pediatric Urology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY; Division of Pediatric Gynecology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY.

Division of Pediatric Urology, Cohen Children's Medical Center, Hofstra Northwell School of Medicine, Long Island, NY.

出版信息

Urology. 2017 Mar;101:151-153. doi: 10.1016/j.urology.2016.12.040. Epub 2016 Dec 28.

DOI:10.1016/j.urology.2016.12.040

PMID:28040504

Abstract

A 12-year-old female presented with abdominal pain, night sweats, weight loss, constipation, dysmenorrhea, menorrhagia, and vaginal discharge. Examination revealed a palpable flank mass and a large tumor adherent to the anterior vaginal wall. Computed tomography scan demonstrated a 23 cm mass in the left kidney, a separate 10.8 cm pelvic mass, and metastatic disease. Biopsies were consistent with Wilms tumor. Neoadjuvant chemotherapy and a left radical nephrectomy were performed for her stage IV disease as the kidney was amiable to complete resection. The patient received radiation and resumed chemotherapy. She was doing well with improved symptoms at follow-up.

摘要

一名12岁女性出现腹痛、盗汗、体重减轻、便秘、痛经、月经过多及阴道分泌物增多症状。检查发现可触及侧腹肿块，且有一个大肿瘤附着于阴道前壁。计算机断层扫描显示左肾有一个23厘米的肿块、一个单独的10.8厘米盆腔肿块及转移性疾病。活检结果与肾母细胞瘤相符。鉴于肾脏适合完整切除，对其IV期疾病进行了新辅助化疗及左肾根治性切除术。患者接受了放疗并继续化疗。随访时她情况良好，症状有所改善。