Bemba E L P, Bopaka R G, Ossibi-Ibara R, Toungou S N, Ossale-Abacka B K, Okemba-Okombi F H, Mboussa J
Faculté des sciences de la santé, université Marien Ngouabi, Brazzaville, Congo; Service de pneumologie, CHU de Brazzaville, BP : 1846, Brazzaville, Congo.
Service de pneumologie, CHU de Brazzaville, BP : 1846, Brazzaville, Congo.
Rev Pneumol Clin. 2017 Apr;73(2):81-89. doi: 10.1016/j.pneumo.2016.11.001. Epub 2016 Dec 29.
The abandonment of TB treatment has consequences both individual by increasing the risk of drug resistance and collective seeding entourage. The aim of this study is to determine the risk factors to be lost sight of during TB treatment.
He acted in a prospective cohort study of patients with microbiologically confirmed tuberculosis, beginning TB treatment and followed for six months. The comparative study between 75 patients lost (PL) and 108 no-patients lost (NPL).
The presence of a large distance between the home center [OR=3.73 (1.21-11.05), P=0.022], to alcohol poisoning [OR=3.80 (3.80-11.3), P=0.031], the number of compressed high (depending on the patient) [OR=7.64 (1.96-29.8), P=0.007], stigma [OR=7.85 (1.87-33), P=0.004] were related to PL status. For against the implementation of the directly observed treatment by the community [OR=0.2 (0.03-0.92), P=0.04], be [OR=0.18 (0.05-0.63), P=0.07] were linked to reduced risk of being lost.
Reducing the rate of PL requires patient compliance with good attitudes in post-education and ease of access to TB centers.
放弃结核病治疗会带来个体层面的后果，即增加耐药风险，也会造成集体层面的后果，即感染周围人群。本研究的目的是确定结核病治疗期间被忽视的风险因素。
对微生物学确诊的结核病患者进行前瞻性队列研究，患者开始结核病治疗并随访6个月。对75例失访患者（PL）和108例未失访患者（NPL）进行对比研究。
家庭住址与治疗中心距离远[比值比（OR）=3.73（1.21 - 11.05），P = 0.022]、酒精中毒[OR = 3.80（3.80 - 11.3），P = 0.031]、合并症数量多（取决于患者）[OR = 7.64（1.96 - 29.8），P = 0.007]、受歧视[OR = 7.85（1.87 - 33），P = 0.004]与失访状态相关。相反，社区实施直接观察治疗[OR = 0.2（0.03 - 0.92），P = 0.04]、有监护人[OR = 0.18（0.05 - 0.63），P = 0.07]与失访风险降低有关。
降低失访率需要患者在教育后保持良好态度并易于前往结核病治疗中心。
