Allergy Associates of the Palm Beaches, North Palm Beach, Fla.
Department of Pediatrics, Section of Immunology Allergy and Rheumatology, Center for Human Immunobiology, Texas Children's Hospital and Baylor College of Medicine, Houston, Tex.
J Allergy Clin Immunol. 2017 Mar;139(3S):S1-S46. doi: 10.1016/j.jaci.2016.09.023. Epub 2016 Dec 29.
Human immunoglobulin preparations for intravenous or subcutaneous administration are the cornerstone of treatment in patients with primary immunodeficiency diseases affecting the humoral immune system. Intravenous preparations have a number of important uses in the treatment of other diseases in humans as well, some for which acceptable treatment alternatives do not exist. We provide an update of the evidence-based guideline on immunoglobulin therapy, last published in 2006. Given the potential risks and inherent scarcity of human immunoglobulin, careful consideration of its indications and administration is warranted.
静脉注射或皮下注射用人免疫球蛋白制剂是治疗影响体液免疫系统的原发性免疫缺陷病患者的基石。静脉注射制剂在治疗人类其他疾病方面也有许多重要用途，其中一些疾病没有可接受的替代治疗方法。我们提供了 2006 年发布的免疫球蛋白治疗循证指南的最新更新。鉴于人免疫球蛋白的潜在风险和固有稀缺性，有必要仔细考虑其适应证和给药方案。
