Orange Jordan S, Hossny Elham M, Weiler Catherine R, Ballow Mark, Berger Melvin, Bonilla Francisco A, Buckley Rebecca, Chinen Javier, El-Gamal Yehia, Mazer Bruce D, Nelson Robert P, Patel Dhavalkumar D, Secord Elizabeth, Sorensen Ricardo U, Wasserman Richard L, Cunningham-Rundles Charlotte
Department of Pediatrics, University of Pennsylvania School of Medicine, The Children's Hospital of Philadelphia, Philadelphia 19104, USA.
J Allergy Clin Immunol. 2006 Apr;117(4 Suppl):S525-53. doi: 10.1016/j.jaci.2006.01.015.
Human immunoglobulin prepared for intravenous administration (IGIV) has a number of important uses in the treatment of disease. Some of these are in diseases for which acceptable treatment alternatives do not exist. In this review we have evaluated the evidence underlying a wide variety of IGIV uses and make specific recommendations on the basis of these data. Given the potential risks and inherent scarcity of IGIV, careful consideration of the indications for and administration of IGIV is warranted.
静脉注射用人免疫球蛋白（IGIV）在疾病治疗中有许多重要用途。其中一些用途针对的是尚无可接受替代治疗方法的疾病。在本综述中，我们评估了IGIV广泛用途背后的证据，并基于这些数据提出了具体建议。鉴于IGIV存在潜在风险且供应天然稀缺，有必要仔细考虑IGIV的适应症和给药方式。
