Rosa-Gonçalves Diana, Bernardes Miguel, Costa Lúcia
Rheumatology Department, Centro Hospitalar São João, Portugal.
Rheumatology Department, Centro Hospitalar São João, Portugal.
Reumatol Clin (Engl Ed). 2018 May-Jun;14(3):168-170. doi: 10.1016/j.reuma.2016.10.008. Epub 2016 Dec 29.
We present a case of necrotizing fasciitis in a 66-year-old Caucasian woman with rheumatoid arthritis receiving tocilizumab, and provide a review of published cases. The patient exhibited no systemic symptoms and discreet cutaneous inflammatory signals at presentation. She was successfully treated with broad-spectrum empiric antibiotic therapy and surgical debridement.
我们报告一例66岁患类风湿关节炎且正在接受托珠单抗治疗的白种女性发生坏死性筋膜炎的病例,并对已发表的病例进行综述。该患者就诊时无全身症状,皮肤炎症信号不明显。她通过广谱经验性抗生素治疗和手术清创得以成功治愈。