Carli A V, Negus J J, Haddad F S
Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
University College London Hospitals, 235 Euston Road, London, NW1 2BU and NIHR University College London Hospitals Biomedical Research Centre, UK.
Bone Joint J. 2017 Jan;99-B(1 Supple A):50-59. doi: 10.1302/0301-620X.99B1.BJJ-2016-0220.R1.
Periprosthetic femoral fractures (PFF) following total hip arthroplasty (THA) are devastating complications that are associated with functional limitations and increased overall mortality. Although cementless implants have been associated with an increased risk of PFF, the precise contribution of implant geometry and design on the risk of both intra-operative and post-operative PFF remains poorly investigated. A systematic review was performed to aggregate all of the PFF literature with specific attention to the femoral implant used.
A systematic search strategy of several journal databases and recent proceedings from the American Academy of Orthopaedic Surgeons was performed. Clinical articles were included for analysis if sufficient implant description was provided. All articles were reviewed by two reviewers. A review of fundamental investigations of implant load-to-failure was performed, with the intent of identifying similar conclusions from the clinical and fundamental literature.
In total 596 articles were initially identified, with 34 being eligible for analysis. Aggregate analysis of 1691 PFFs in 342 719 primary THAs revealed a significantly higher number of PFFs with cementless femoral implants (p < 0.001). Single-wedge and double-wedge (fit-and-fill) femoral implants were associated with a threefold increase in PFF rates (p < 0.001) compared with anatomical, fully coated and tapered/rounded stems. Within cemented stems, loaded-taper (Exeter) stems were associated with more PFFs than composite-beam (Charnley) stems (p = 0.004). Review of the fundamental literature revealed very few studies comparing cementless component designs.
Very few studies within the PFF literature provide detailed implant information. Cementless implants, specifically those of single-wedge and double-wedge, have the highest PFF rates in the literature, with most investigations recommending against their use in older patients with osteoporotic bone. This review illustrates the need for registries and future PFF studies to record implant name and information for future analysis. Furthermore, future biomechanical investigations comparing modern implants are needed to clarify the precise contribution of implant design to PFF risk. Cite this article: Bone Joint J 2017;99-B(1 Supple A):50-9.
全髋关节置换术(THA)后假体周围股骨骨折(PFF)是一种严重的并发症,与功能受限及总体死亡率增加相关。尽管非骨水泥型植入物与PFF风险增加有关,但植入物几何形状和设计对术中及术后PFF风险的确切影响仍研究不足。本研究进行系统评价,汇总所有关于PFF的文献,并特别关注所使用的股骨植入物。
对多个期刊数据库及美国骨科医师学会近期会议论文进行系统检索。若文章提供了足够的植入物描述,则纳入分析。所有文章由两名审阅者进行审阅。对植入物失效载荷的基础研究进行综述,旨在从临床和基础文献中找出相似结论。
最初共识别出596篇文章,其中34篇符合分析条件。对342719例初次THA中的1691例PFF进行汇总分析,结果显示非骨水泥型股骨植入物导致的PFF数量显著更多(p<0.001)。与解剖型、全涂层型及锥形/圆形柄相比,单楔和双楔(贴合填充型)股骨植入物的PFF发生率增加了两倍(p<0.001)。在骨水泥柄中,加载锥形(埃克塞特)柄导致的PFF比复合梁(查恩利)柄更多(p=0.004)。对基础文献的综述显示很少有研究比较非骨水泥部件设计。
PFF文献中很少有研究提供详细的植入物信息。非骨水泥型植入物,特别是单楔和双楔型,在文献中的PFF发生率最高,大多数研究建议老年骨质疏松患者不要使用。本综述表明登记系统及未来的PFF研究需要记录植入物名称和信息以供未来分析。此外,需要进行比较现代植入物的未来生物力学研究,以明确植入物设计对PFF风险的确切影响。引用本文:《骨与关节杂志》2017年;99-B(增刊A):50-9。