长春氟宁治疗晚期尿路上皮癌：临床证据与经验
Vinflunine in the treatment of advanced urothelial cancer: clinical evidence and experience.
作者信息
Gerullis Holger, Wawroschek Friedhelm, Köhne Claus-Henning, Ecke Thorsten Holger
机构信息
University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Rahel-Straus-Straße 10, 26133 Oldenburg, Germany.
University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Germany.
出版信息
Ther Adv Urol. 2017 Jan;9(1):28-35. doi: 10.1177/1756287216677903. Epub 2016 Nov 21.
Abstract
Vinflunine (VFL) has been approved in Europe for second-line treatment of metastatic and advanced urothelial cancer after failure of platin-containing therapy. Since approval, the drug has been investigated in few clinical trials. Most of the currently available reports describe experiences with VFL in a daily clinical setting. This review gives a short overview on clinical experiences and clinical trials involving VFL since the approval of this drug in 2009.
摘要
长春氟宁（VFL）已在欧洲获批用于含铂疗法失败后的转移性和晚期尿路上皮癌的二线治疗。自获批以来，该药物仅在少数临床试验中进行了研究。目前大多数现有报告描述了VFL在日常临床环境中的应用经验。本综述简要概述了自2009年该药物获批以来涉及VFL的临床经验和临床试验。
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