Liu Huan, Wang Hongyu
Department of Vascular Medicine, Peking University Shougang Hospital, Beijing 100144, China.
Biomed Res Int. 2016;2016:1723485. doi: 10.1155/2016/1723485. Epub 2016 Nov 30.
Markers of imaging, structure, and function reflecting vascular damage, integrating a long time accumulation effect of traditional and unrecognized cardiovascular risk factors, can be regarded as surrogate endpoints of target organ damage before the occurrence of clinical events. Prevention of cardiovascular disease requires risk stratification and treatment of traditional risk factors, such as smoking, hypertension, hyperlipidemia, and diabetes. However, traditional risk stratification is not sufficient to provide accurate assessment of future cardiovascular events. Therefore, vascular injury related parameters obtained by ultrasound or other noninvasive devices, as a surrogate parameter of subclinical cardiovascular disease, can improve cardiovascular risk assessment and optimize the preventive treatment strategy. Thus, we will summarize the research progress and clinical application of early assessment technology of vascular diseases in the present review.
反映血管损伤的影像学、结构和功能标志物,整合了传统和未被认识的心血管危险因素的长期累积效应,可被视为临床事件发生前靶器官损伤的替代终点。预防心血管疾病需要对传统危险因素进行风险分层和治疗,如吸烟、高血压、高脂血症和糖尿病。然而,传统的风险分层不足以准确评估未来心血管事件。因此,通过超声或其他无创设备获得的血管损伤相关参数,作为亚临床心血管疾病的替代参数,可改善心血管风险评估并优化预防治疗策略。因此,我们将在本综述中总结血管疾病早期评估技术的研究进展和临床应用。