Cardiological Unit, "Giovanni Paolo II" Hospital, Policoro, Italy.
Cardiological Unit, Cardiovascular Disease Section, Department of Organ Trasplantation, University of Bari, Bari, Italy.
J Hum Hypertens. 2020 Jun;34(6):420-431. doi: 10.1038/s41371-020-0307-7. Epub 2020 Feb 10.
Arterial hypertension is a systemic condition characterized by elevated blood pressure in the vascular system. Despite the great effort of scientific community to sensitize population to the problem, enforcing the preventive and treatment measures, this condition continues to be responsible for a large portion of global mortality, as it represents one of the major modifiable risk factors of cardiovascular disease. The significant and substantial clinical implications of high blood pressure on cardiovascular morbidity and mortality are explained by the effect of hypertension on specific organs, particularly sensitive to the effects of changes in blood pressure, resulting cardiac remodeling, cerebrovascular disease, renal failure, atherosclerotic vascular disease, and retinopathy, hence the term "target organ damage". The aim of this review is to give an overview of several noninvasive tools useful in the detection of organ damage related to arterial hypertension.
动脉高血压是一种全身性疾病,其特征是血管系统中的血压升高。尽管科学界为了使人们意识到这个问题并加强预防和治疗措施付出了巨大努力,但这种情况仍然是导致全球死亡率的主要原因之一,因为它是心血管疾病的主要可改变危险因素之一。高血压对心血管发病率和死亡率的显著和实质性临床影响可以通过高血压对特定器官的影响来解释,这些器官对血压变化的影响特别敏感,导致心脏重构、脑血管疾病、肾衰竭、动脉粥样硬化血管疾病和视网膜病变,因此有了“靶器官损伤”这一术语。本文的目的是概述几种有助于检测与动脉高血压相关的器官损伤的非侵入性工具。