[Effects of immune lymph node factors on formation of immunological memory].

Two various fractions have been formed on the sephadex G-200 from culture supernatants of the lymph nodes cells isolated in 6h after immunization of animals by various antigens. The first fraction possessed the main biological properties peculiar to the earlier described factor of the immune lymph nodes (FILN), intensified proliferation of cells of the popliteal lymph nodes and increased the killer activity of peritoneal lymphocytes. Introduction of FILN simultaneously with ram erythrocytes led to more than a five-fold increase of humoral immune response.