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经尿道前列腺切除术后经闭孔后尿道男性吊带的长期疗效

Long-term Outcome of the Retrourethral Transobturator Male Sling After Transurethral Resection of the Prostate.

作者信息

Kretschmer Alexander, Buchner Alexander, Leitl Benedikt, Grabbert Markus, Sommer Anne, Khoder Wael, Gozzi Christian, Stief Christian G, Bauer Ricarda M

机构信息

Department of Urology, Ludwig-Maximilians-University, Munich, Germany.

Department of Urological Sciences, Vancouver Prostate Centre, University of British Columbia, Vancouver, Canada.

出版信息

Int Neurourol J. 2016 Dec;20(4):335-341. doi: 10.5213/inj.1632648.324. Epub 2016 Dec 26.

Abstract

PURPOSE

To evaluate long-term outcomes of AdVance and AdVanceXP male slings in patients with persistent stress urinary incontinence (SUI) after transurethral resection of the prostate (TURP).

METHODS

A total of 18 consecutive patients received AdVance (n=14) or AdVanceXP (n=4) male sling implantation between 2007 and 2013. Continence was determined by pad use, 24-hour pad testing and validated questionnaires (International Consultation on Incontinence Questionnaire Short Form, ICIQ-SF). Quality of life was evaluated by International Quality of Life (IQoL) score. Patient satisfaction was measured with patient's global impression of improvement score. Cure was defined as 0-5 g in the 24-hour pad test. Statistical analysis included Fisher exact and Wilcoxon test (P<0.05).

RESULTS

Follow-up was available for 15 patients who underwent further analysis. After a median follow-up of 70 months (range, 18-83 months), mean daily pad usage was 1.8±2.1 pads (P=0.015 vs. baseline level). Mean IQoL score was 66.4±31.6 (P=0.050 vs. baseline level), and mean ICIQ-SF score was 9.5±6.6 (P=0.077 vs. baseline level). Based on 24-hour pad testing, mean daily urine loss was 31.2±64.5 g (median, 0 g; range, 0-209 g). Cure rate was 46.7%, and cure-and-improved rate was 60.0%. Assessing predictive features for success, better results were found in patients who needed up to 4 pads preoperatively (P=0.041) as well as for patients ≤71 years at the time of implantation (P=0.041).

CONCLUSIONS

The findings indicate that AdVance and AdVanceXP implantation can be performed effectively and safely in men suffering from SUI after TURP. However, long-term success rates seem to be lower compared to SUI after radical prostatectomy and patients should be counseled accordingly.

摘要

目的

评估AdVance和AdVanceXP男性吊带对经尿道前列腺切除术(TURP)后持续性压力性尿失禁(SUI)患者的长期疗效。

方法

2007年至2013年期间,共有18例连续患者接受了AdVance(n = 14)或AdVanceXP(n = 4)男性吊带植入术。通过使用尿垫、24小时尿垫测试和经过验证的问卷(国际尿失禁咨询问卷简表,ICIQ - SF)来确定尿失禁情况。通过国际生活质量(IQoL)评分评估生活质量。用患者对改善情况的总体印象评分来衡量患者满意度。治愈定义为24小时尿垫测试漏尿量为0 - 5克。统计分析包括Fisher精确检验和Wilcoxon检验(P < 0.05)。

结果

15例患者可供随访并进行进一步分析。中位随访70个月(范围18 - 83个月)后,平均每日尿垫使用量为1.8±2.1片(与基线水平相比,P = 0.015)。平均IQoL评分为66.4±31.6(与基线水平相比,P = 0.050),平均ICIQ - SF评分为9.5±6.6(与基线水平相比,P = 0.077)。基于24小时尿垫测试,平均每日尿量损失为31.2±64.5克(中位数为0克;范围为0 - 209克)。治愈率为46.7%,治愈加改善率为60.0%。评估成功的预测特征发现,术前需要最多4片尿垫的患者(P = 0.041)以及植入时年龄≤71岁的患者(P = 0.041)效果更好。

结论

研究结果表明,对于TURP后患有SUI的男性,AdVance和AdVanceXP植入术可以有效且安全地进行。然而,与根治性前列腺切除术后的SUI相比,长期成功率似乎较低,应相应地对患者进行咨询。

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