Dobrynin V P, Fedan V A, Orbachesvskaia I Iu, Pogozheva E N, Neprintseva E S
Biull Eksp Biol Med. 1989 Aug;108(8):139-42.
Characteristics of regulatory effects of B-activin and thymosin (fraction 5) on the activity of right and left hemispheres were studied in rats. The results obtained were estimated basing on the analysis of the following components of food-searching behavior: lateralization of a single conditioned-reflex response; preference of right or left paw; spontaneous rotations. Opposite effects of thymosin and B-activin were found at different stages of the food-searching behavior. Thymosin activated structures of the left hemisphere. A conclusion is made on the possibility of application of these drugs for targeted influencing the balance of intra-hemispheric activity in the brain functional pathology and during the compensatory process.
研究了β-激活素和胸腺素(5组分)对大鼠左右半球活动的调节作用特征。基于对觅食行为以下组成部分的分析来评估所得结果:单个条件反射反应的偏侧化;右爪或左爪偏好;自发旋转。在觅食行为的不同阶段发现胸腺素和β-激活素具有相反的作用。胸腺素激活左半球结构。得出结论,这些药物有可能用于在脑功能病理学和代偿过程中靶向影响脑内半球活动的平衡。