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[海马体在通过尾状核电刺激引发惊厥综合征发展过程中的意义]

[Significance of the hippocampus in the development of convulsive syndrome by kindling electrostimulation of the caudate nucleus].

作者信息

Timofeeva O A

出版信息

Biull Eksp Biol Med. 1989 Aug;108(8):145-7.

PMID:2804315
Abstract

The experiments were conducted on rabbits with chronically implanted electrodes (neocortex, hippocampus, amygdala, caudate nucleus). The rostral part of caudate nucleus was stimulated once daily at a current maximum 300 microA, using 60 Hz square pulses (1.0 Ms) 12.0 s in duration. The severity of motor seizures and its developmental velocity were studied in the relation with a degree of the epileptization of the brain. The data obtained illustrated the next relation: the more stable and intensive were discharges in hippocampus the harder motor seizures.

摘要

实验在长期植入电极(新皮层、海马体、杏仁核、尾状核)的兔子身上进行。使用60赫兹方波脉冲(1.0毫秒),持续时间12.0秒,每天一次以最大300微安的电流刺激尾状核的嘴侧部分。研究了运动性癫痫发作的严重程度及其发展速度与大脑癫痫化程度的关系。所获得的数据表明了以下关系:海马体中的放电越稳定、越强烈,运动性癫痫发作就越严重。

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[Significance of the hippocampus in the development of convulsive syndrome by kindling electrostimulation of the caudate nucleus].[海马体在通过尾状核电刺激引发惊厥综合征发展过程中的意义]
Biull Eksp Biol Med. 1989 Aug;108(8):145-7.
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[The central structural interrelations during kindling electrostimulations of the hippocampus].[海马体点燃式电刺激期间的中枢结构相互关系]
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