Timofeeva O A
Biull Eksp Biol Med. 1989 Aug;108(8):145-7.
The experiments were conducted on rabbits with chronically implanted electrodes (neocortex, hippocampus, amygdala, caudate nucleus). The rostral part of caudate nucleus was stimulated once daily at a current maximum 300 microA, using 60 Hz square pulses (1.0 Ms) 12.0 s in duration. The severity of motor seizures and its developmental velocity were studied in the relation with a degree of the epileptization of the brain. The data obtained illustrated the next relation: the more stable and intensive were discharges in hippocampus the harder motor seizures.
实验在长期植入电极(新皮层、海马体、杏仁核、尾状核)的兔子身上进行。使用60赫兹方波脉冲(1.0毫秒),持续时间12.0秒,每天一次以最大300微安的电流刺激尾状核的嘴侧部分。研究了运动性癫痫发作的严重程度及其发展速度与大脑癫痫化程度的关系。所获得的数据表明了以下关系:海马体中的放电越稳定、越强烈,运动性癫痫发作就越严重。