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[δ-促睡眠肽对实验性癫痫期间中枢间整合的影响]

[Effects of delta sleep-inducing peptide on the intercentral integration during experimental epilepsy].

作者信息

Popova N S, Adrianov O S, Veskov R, Iankovich B, Rakich L

出版信息

Biull Eksp Biol Med. 1989 Aug;108(8):147-50.

PMID:2804316
Abstract

In free behavior experiments on cats it has been shown, that the intraperitoneal injection of delta-sleep-inducing peptide (100 mg/kg) may change organization of the pathology integration-epileptic discharges did not spread all the structures simultaneously. The slow-waves were registered in central medium of the thalamus and nucl. caudati. The epileptic discharges were registered first in visual and auditory cortex, hippocampus. After that they were observed in the motor cortex, nucl. caudati and centrum medianum of the thalamus.

摘要

在对猫进行的自由行为实验中已表明,腹腔注射δ-睡眠诱导肽(100毫克/千克)可能会改变病理整合的组织——癫痫放电并非同时扩散到所有结构。在丘脑中央介质和尾状核中记录到了慢波。癫痫放电首先在视觉和听觉皮层、海马体中记录到。之后在运动皮层、尾状核和丘脑中央中核中观察到。

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