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[Effect of the delta sleep peptide on epileptic activity in the cerebral cortex of rats and cats].

作者信息

Kryzhanovskiĭ G N, Shandra A A, Godlevskiĭ L S, Karpova M N, Mikhaleva I I

出版信息

Biull Eksp Biol Med. 1987 Nov;104(11):582-5.

PMID:3676495
Abstract

In free behaviour experiments on rats it has been shown that the intraperitoneal injection of delta sleep-inducing peptide (DSIP) (100 micrograms/kg) suppressed penicillin-induced relatively moderate epileptic foci which generated spike potentials as well as severe foci with ictal epileptic discharges. In the experiments on cats it was shown that intravenous DSIP injection (100 micrograms/kg) suppressed strychnine-induced epileptic focus and complexes of epileptic foci.

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