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经皮内镜下腰椎间盘摘除术后复发性疝出的危险因素

Risk Factors for Recurrent Herniation After Percutaneous Endoscopic Lumbar Discectomy.

作者信息

Yao Yuan, Liu Huan, Zhang Huiyu, Wang Honggang, Zhang Chao, Zhang Zhengfeng, Wu Junlong, Tang Yu, Zhou Yue

机构信息

Department of Orthopedics, Xinqiao Hospital, Third Military Medical University, Chongqing, China.

Department of Stomatology, 457th Hospital of PLA, Wuhan, China.

出版信息

World Neurosurg. 2017 Apr;100:1-6. doi: 10.1016/j.wneu.2016.12.089. Epub 2016 Dec 30.

Abstract

BACKGROUND

Percutaneous endoscopic lumbar discectomy (PELD) has been widely used for treating lumbar disc herniation. Recurrence after PELD has been reported, but few studies have focused on the risk factors responsible for recurrence after PELD.

METHODS

This retrospective study enrolled 116 patients with recurrent herniation after successful PELD from March 2005 to March 2016. Kaplan-Meier method and Cox regression analysis were employed to identify significant risk factors predicting recurrence after PELD.

RESULTS

Univariate analysis showed that older age (≥50 years old), obesity (body mass index ≥25), no smoking history, decreased reflexes, learning curve of the surgeon (<200 cases), treatment period (March 2005 to September 2010), Modic change, migrated herniation, and central herniation are potential risk factors for recurrence after PELD. Multivariate analysis suggested that older age (≥50 years old), obesity (body mass index ≥25), learning curve of the surgeon (<200 cases), treatment period (March 2005 to September 2010), and central location of herniation are independent significant risk factors for recurrence after PELD.

CONCLUSIONS

Obesity (body mass index ≥25) was the most robust risk factor responsible for recurrence after PELD. Older age (≥50 years old), learning curve of the surgeon (<200 cases), treatment period (March 2005 to September 2010), and central location of herniation were also closely associated with recurrent herniation after successful PELD.

摘要

背景

经皮内镜下腰椎间盘切除术(PELD)已广泛用于治疗腰椎间盘突出症。已有PELD术后复发的报道,但很少有研究关注PELD术后复发的危险因素。

方法

这项回顾性研究纳入了2005年3月至2016年3月期间116例PELD成功后复发的患者。采用Kaplan-Meier法和Cox回归分析来确定预测PELD术后复发的显著危险因素。

结果

单因素分析显示,年龄较大(≥50岁)、肥胖(体重指数≥25)、无吸烟史、反射减弱、术者学习曲线(<200例)、治疗时期(2005年3月至2010年9月)、Modic改变、游离型突出及中央型突出是PELD术后复发的潜在危险因素。多因素分析表明,年龄较大(≥50岁)、肥胖(体重指数≥25)、术者学习曲线(<200例)、治疗时期(2005年3月至2010年9月)及突出位于中央是PELD术后复发的独立显著危险因素。

结论

肥胖(体重指数≥25)是PELD术后复发最有力的危险因素。年龄较大(≥50岁)、术者学习曲线(<200例)、治疗时期(2005年3月至2010年9月)及突出位于中央也与PELD成功后复发密切相关。

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