Bertleff-Zieschang Nadja, Rahim Md Arifur, Ju Yi, Braunger Julia A, Suma Tomoya, Dai Yunlu, Pan Shuaijun, Cavalieri Francesca, Caruso Frank
Australian Research Council (ARC) Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.
Chem Commun (Camb). 2017 Jan 17;53(6):1068-1071. doi: 10.1039/c6cc08607a.
We assembled dietary, bioactive flavonoids into a metal coordinated network to form thin, surface-bound films and hollow capsules, overcoming the poor water solubility of free flavonoids. Films formed from quercetin, myricetin, luteolin and fisetin show radical scavenging activity, a renowned feature of their parent flavonoids, and can be reused over multiple cycles. These films are expected to have potential applications in the pharmaceutical and food industries.
我们将膳食生物活性类黄酮组装成金属配位网络，以形成薄的表面结合膜和中空胶囊，克服了游离类黄酮水溶性差的问题。由槲皮素、杨梅素、木犀草素和非瑟酮形成的膜具有自由基清除活性，这是其母体类黄酮的一个著名特性，并且可以多次重复使用。这些膜有望在制药和食品工业中具有潜在应用。
