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术后出血性闭塞性视网膜血管炎:一种顿挫型变体?

POSTOPERATIVE HEMORRHAGIC OCCLUSIVE RETINAL VASCULITIS: A FORME FRUSTE VARIANT?

作者信息

Goldberg Roger A, Crawford Courtney, Heier Jeffrey S

机构信息

Bay Area Retina Associates, Walnut Creek, California.

Ophthalmic Consultants of Boston, Boston, Massachusetts.

出版信息

Retin Cases Brief Rep. 2018;12(4):305-306. doi: 10.1097/ICB.0000000000000514.

Abstract

PURPOSE

To present a forme fruste variant of hemorrhagic occlusive retinal vasculitis (HORV) after uncomplicated cataract surgery performed with vancomycin in the irrigating solution.

METHODS

A report of a single patient who developed HORV; the clinical features and course are described and compared with previously reported cases.

RESULTS

Ultra-widefield fluorescein angiography demonstrated an occlusive vasculitis in both eyes 1 week after uncomplicated cataract surgery in which vancomycin was added to the irrigating solution. An extensive systemic evaluation including a hypercoagulable workup, serum electrophoresis, complete blood count, and carotid and cardiac ultrasound was negative. Visual acuity was unaffected, and the patient remained 20/20 in each eye one year after surgery without treatment. This is a markedly different outcome than seen in previously reported cases of HORV.

CONCLUSION

Ultra-widefield angiography was helpful to confirming the diagnosis of HORV in this milder case example in a patient who maintained excellent vision. This forme fruste variant of HORV after exposure to vancomycin suggests that the incidence of HORV after cataract surgery may be more common than previously reported. Vigilance, close observation, and broad reporting can help further clarify the incidence and potential adverse effects of routinely using intracameral vancomycin during cataract surgery.

摘要

目的

介绍在冲洗液中使用万古霉素进行单纯白内障手术后出现的出血性闭塞性视网膜血管炎(HORV)的顿挫型变体。

方法

报告一例发生HORV的患者;描述其临床特征和病程,并与先前报道的病例进行比较。

结果

超广角荧光素血管造影显示,在单纯白内障手术后1周,双眼出现闭塞性血管炎,术中冲洗液中添加了万古霉素。包括高凝检查、血清电泳、全血细胞计数以及颈动脉和心脏超声在内的全面系统评估均为阴性。视力未受影响,患者术后一年未经治疗,每只眼视力仍保持在20/20。这一结果与先前报道的HORV病例明显不同。

结论

超广角血管造影有助于在该视力保持良好的较轻病例中确诊HORV。接触万古霉素后出现的这种HORV顿挫型变体表明,白内障手术后HORV的发生率可能比先前报道的更为常见。保持警惕、密切观察并广泛报告有助于进一步明确白内障手术中常规使用前房内万古霉素的发生率和潜在不良反应。

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