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一例双侧出血性闭塞性视网膜血管炎患者尽管早期进行了干预,但病情仍迅速且进行性恶化。

Rapid and progressive decline despite early intervention in a case of bilateral hemorrhagic occlusive retinal vasculitis.

作者信息

Motlagh Mahsaw N, Javid Cameron G

机构信息

Department of Ophthalmology, University of Arizona College of Medicine, Tucson, AZ, USA.

出版信息

Am J Ophthalmol Case Rep. 2020 Jan 14;17:100595. doi: 10.1016/j.ajoc.2020.100595. eCollection 2020 Mar.

Abstract

PURPOSE

To present a case of severe bilateral hemorrhagic occlusive retinal vasculitis (HORV) after uncomplicated cataract surgery with intracameral vancomycin. We present a report of a single patient with bilateral presentation of HORV that demonstrated classic features of the disease and progressed to profound vision loss despite early and aggressive intervention.

OBSERVATIONS

On initial presentation, the patient had good Snellen visual acuity of 20/25 PH 20/20 OD and 20/60 PH 20/30 OS with retinal hemorrhages in both eyes and sub-hyaloid hemorrhage in the left eye. Early therapeutic intervention with intravitreal corticosteroids, anti-vascular endothelial growth factor (anti-VEGF) agents and oral steroids was pursued. Even with treatment, the clinical picture rapidly deteriorated with progression of occlusive and hemorrhagic complications in both eyes resulting in bilateral ischemic retinopathy and breakthrough vitreous hemorrhage. After a prolonged course of treatment including the aforementioned along with panretinal photocoagulation (PRP) in both eyes and vitreoretinal surgery in the left eye, the final visual acuity was light perception (LP) OD and 20/100 OS.

CONCLUSIONS AND IMPORTANCE

Hemorrhagic occlusive retinal vasculitis remains a feared complication of uncomplicated cataract surgery utilizing intracameral vancomycin. Despite early recognition and appropriate intervention, our patient still had a poor visual outcome with significant ischemic damage.

摘要

目的

报告一例在单纯白内障手术中使用前房内万古霉素后发生的严重双侧出血性闭塞性视网膜血管炎(HORV)病例。我们报告了一名双侧HORV患者,其表现出该疾病的典型特征,尽管进行了早期积极干预,但仍进展为严重视力丧失。

观察结果

初诊时,患者的最佳矫正视力良好,右眼为20/25 针孔视力20/20,左眼为20/60 针孔视力20/30,双眼均有视网膜出血,左眼有玻璃膜下出血。采用玻璃体内注射皮质类固醇、抗血管内皮生长因子(抗VEGF)药物和口服类固醇进行早期治疗干预。即使经过治疗,随着双眼闭塞性和出血性并发症的进展,临床情况迅速恶化,导致双侧缺血性视网膜病变和玻璃体积血突破。经过包括上述治疗以及双眼全视网膜光凝(PRP)和左眼玻璃体视网膜手术在内的长期治疗过程,最终视力右眼为光感(LP),左眼为20/100。

结论与意义

出血性闭塞性视网膜血管炎仍然是在单纯白内障手术中使用前房内万古霉素后令人担忧的并发症。尽管早期识别并进行了适当干预,但我们的患者仍视力不佳,有明显的缺血性损害。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4052/6974737/cdaadcfacc19/gr1.jpg

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