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[硬膜外镇痛对分娩的影响]

[Effects of peridural analgesia on labor].

作者信息

Durand G, Viala J L, Jullien Y, Nicolas J, D'Athis F

出版信息

Ann Anesthesiol Fr. 1978;19(4):236-40.

PMID:28046
Abstract

A review of the effects during labour of epidural analgesia on dilatation, expulsion and delivery of the placenta. Uncertainties in knowledge of the precise organisation of uterine innervation and of the intrinsic innervation of the organ render the study of changes in uterine contraction and in cervical resistances difficult. At circulating levels higher than those found in clinical practice, local anaesthetics have a definite oxytocic e-fect, local anaesthetics have a definite oxytoci effect, whilst adrenalin is a powerfult tocolytic. By contrast, the indirect effects related to neurolysis in extradural analgesia are negligeable. Cervico-segmentary resistances are decreased. In practice, there is no increase in the period of dilatation in the absence of any haemodynamic disturbances and if mixtures containing adrenalin are avoided. Expulsion is favourised by muscular relaxation but impaired by the lack of voluntary expulsive effort, hence the choice of a local anaesthetic with the lowest possible motor effect. Delivery of the placenta, which involves only uterine contraction, which is not affected, may be accelerated by oxytocics.

摘要

硬膜外镇痛对分娩过程中胎盘扩张、娩出和分娩影响的综述。子宫神经支配的确切组织结构以及该器官的内在神经支配方面的知识不确定性,使得研究子宫收缩和宫颈阻力的变化变得困难。在高于临床实践中发现的循环水平时,局部麻醉药具有明确的催产作用,而肾上腺素是一种强大的宫缩抑制剂。相比之下,硬膜外镇痛中与神经溶解相关的间接影响可忽略不计。宫颈节段阻力降低。实际上,在没有任何血流动力学干扰且避免使用含肾上腺素混合物的情况下,扩张期不会延长。肌肉松弛有利于娩出,但缺乏自主娩出力会损害娩出,因此选择运动效应尽可能低的局部麻醉药。仅涉及子宫收缩且不受影响的胎盘娩出,可通过催产素加速。

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