Sarfati E, Desportes L, Gossot D, Dubost C
Department of Visceral Surgery, Hôpital Saint Louis, Paris, France.
Br J Surg. 1989 Sep;76(9):979-81. doi: 10.1002/bjs.1800760937.
Acute primary hyperparathyroidism is a rare disease with a high mortality rate in some series. Between 1960 and 1986, 1000 patients were treated for primary hyperparathyroidism, among them 59 patients with acute hyperparathyroidism. All these patients were successfully operated on; none of them died before surgery. This study reveals the importance of resuscitation and urgent surgery. It is necessary to rehydrate, to correct electrolyte disorders and to lower serum calcium levels, but it is not necessary to obtain normal serum calcium levels before surgery.
急性原发性甲状旁腺功能亢进是一种罕见疾病,在某些系列研究中死亡率较高。1960年至1986年间,1000例患者接受了原发性甲状旁腺功能亢进的治疗,其中59例为急性甲状旁腺功能亢进患者。所有这些患者均成功接受了手术;术前无一人死亡。本研究揭示了复苏和紧急手术的重要性。补液、纠正电解质紊乱和降低血清钙水平是必要的,但术前无需将血清钙水平恢复正常。