Herman William H
W.H. Herman is with the Department of Internal Medicine and Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Nutr Rev. 2017 Jan;75(suppl 1):13-18. doi: 10.1093/nutrit/nuw034.
Diabetes represents an enormous and growing clinical and public health problem. Its financial burden is huge and growing and likely to be unsustainable. Lifestyle interventions are safe and effective for preventing diabetes, are associated with improved quality of life, and are cost-effective. Metformin is effective, safe, and cost-effective, if not cost-saving. National and international efforts are needed to identify at-risk individuals and to systematically apply these interventions. Research must focus on how best to implement diabetes prevention in diverse populations and settings.
糖尿病是一个巨大且不断发展的临床和公共卫生问题。其经济负担巨大且不断增加,可能难以持续。生活方式干预对预防糖尿病安全有效,能改善生活质量,且具有成本效益。二甲双胍有效、安全且具有成本效益,甚至可能节省成本。需要国家和国际层面的努力来识别高危个体并系统地应用这些干预措施。研究必须聚焦于如何在不同人群和环境中最佳地实施糖尿病预防。