Rossi L N, Vassella F
Department of Pediatrics, University of Bern, Switzerland.
Childs Nerv Syst. 1989 Oct;5(5):307-9. doi: 10.1007/BF00274519.
To study the criteria for early differential diagnosis between migraine and headache due to brain tumors, we analyzed the symptoms and signs of two groups of children. The first group consisted of 67 children in whom a brain tumor had been diagnosed. The second group was composed of 600 children who had been diagnosed as migraine cases. Among the features of headache that are considered to be alarming symptoms of a brain tumor, the following were found to indicate a brain tumor with the greatest sensitivity: nocturnal headache or headache present on arising, both associated with vomiting, and increased frequency of headache. Nocturnal headache or headache present on arising, associated with vomiting, and/or progressive neurological symptoms or signs occurred in 65 of 67 children with brain tumor within 2 months of the onset of their headaches and in all 67 within 6 months.
为研究偏头痛与脑肿瘤所致头痛的早期鉴别诊断标准，我们分析了两组儿童的症状和体征。第一组由67例已诊断为脑肿瘤的儿童组成。第二组由600例已诊断为偏头痛的儿童组成。在被认为是脑肿瘤警示症状的头痛特征中，发现以下特征对脑肿瘤的指示敏感性最高：夜间头痛或晨起时头痛，两者均伴有呕吐，以及头痛频率增加。67例脑肿瘤患儿中，65例在头痛发作后2个月内出现夜间头痛或晨起时头痛并伴有呕吐，和/或进行性神经症状或体征，67例在6个月内均出现上述情况。
